Childhood asthma and puberty.

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Childhood asthma and puberty.

Thirty eight, chronic, perennial asthmatic children were prospectively examined every six months for a mean 8.9 years to clarify the relation between clinical asthma and puberty. Improvement in the disease occurred independent of puberty but the rate of improvement was appreciably greater during puberty. This led to speculation that improvement in childhood asthma could be associated with an im...

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IL-23 Gene and Protein Expression in Childhood Asthma

Background: Asthma is the chronic inflammation of airways characterized by eosinophilic infiltration, mucus overproduction, airway hyper-responsiveness and airway remodeling. These changes are induced mostly by cytokines which are produced by T helper (Th) 2 cells. Recently, the role of interleukin-23 (IL-23) in the pathogenesis of adultallergic asthma has been studied. Objective: To explore IL...

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Growth and childhood asthma.

Correspondence Growth and childhood asthma Sir, We read the recent article by Dr Balfour-Lynn with interest.1 In this study the prepubertal height centile from a 'distance' chart of each individual child was extrapolated to the adult centile as an assessment of final height prognosis. It is the degree of epiphysial maturation, however, that determines the proportion of growth that has occurred ...

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Growth and childhood asthma.

Height and weight were measured every six months in a long term prospective study of 66 children with chronic perennial asthma for a mean 13.1 years. There was no evidence of growth retardation on entry into the study. Growth developed along normal lines in all 66 children until about 10 years, and in 35 of these children growth continued along normal lines throughout the whole period of follow...

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Childhood asthma.

Asthma prevalence in children has increased 58% since 1980. Mortality has increased by 78%. The burden of the disease is most acute in urban areas and racial/ethnic minority populations. Hospitalization and morbidity rates for nonwhites are more than twice those for whites. Asthma is characterized by recurrent wheezing, breathlessness, chest tightness, and coughing. Research in the past decade ...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1985

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.60.3.231